Несостоятельности трансплантата у реципиентов аллогенных гемопоэтических стволовых клеток: диагностика и лечение

Автор: Масликова У. В., Попова Н. Н., Дроков М. Ю., Хамаганова Е. Г.

Журнал: Вестник медицинского института "РЕАВИЗ": реабилитация, врач и здоровье @vestnik-reaviz

Рубрика: Донорство и трансплантация органов и тканей

Статья в выпуске: 1 т.13, 2023 года.

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Несостоятельность трансплантата - группа осложнений после трансплантации аллогенных гемопоэтических стволовых клеток, которая встречается по разным данным до 30 % случаев. В группу осложнений входят первичная и вторичная несостоятельность трансплантата, первичная, вторичная и транзиторная гипофункция трансплантата и отторжение трансплантата. Сложности диагностики заключаются в отсутствии единых критериев, принятых в трансплантационном сообществе, и в двоякой интерпретации этих осложнений по данным иностранной литературы. Целью данного обзора литературы было определить наиболее часто встречающиеся критерии различных видов несостоятельности трансплантата и тактику диагностики и лечения. В обзоре мы проанализировали данные различных источников литературы, дали определения несостоятельности и гипофункции трансплантата, проанализировали литературные данные по применяемым методам лечения данных состояний.

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Трансплантация аллогенных гемопоэтических стволовых клеток, алло-тгск, несостоятельность трансплантата, гипофункция трансплантата

Короткий адрес: https://sciup.org/143179922

IDR: 143179922   |   DOI: 10.20340/vmi-rvz.2023.1.TX.1

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