Non-alcoholic fatial diseases of the liver: historical aspect of the formation of nosological unit, etiology and pathogenetic peculiarities of this pathology (literature review)
Автор: Mosina Larisa, Korobkov Denis, Mokina E., Kumanyaeva D., Rakhmatullina M.
Журнал: Бюллетень науки и практики @bulletennauki
Рубрика: Медицинские науки
Статья в выпуске: 12 т.4, 2018 года.
Бесплатный доступ
This literature review focuses on non-alcoholic fatty liver disease (NAFTLD). Today, the world practice of researching diseases is characterized by a multifactor approach, in particular, it concerns pathologies, which are based on a cascade of metabolic disorders, where insulin resistance is one of the key places. Today, NAFTLD is considered an integral part of the metabolic syndrome. The frequency of occurrence of NAFTLD varies from 14 to 26%, in addition, 10% of patients show signs of steatohepatitis non-alcoholic etiology. The pathogenesis of steatosis and metabolic steatohepatitis is poorly studied and there are very contradictory data in the literature, which served as the basis for the creation of this review. The authors consider in detail the historical aspect of the formation of the NAFTLD as an independent nosological unit. A number of etiological aspects of the formation of NAFTLD, but to a large extent, the review is devoted to the mechanisms and pathogenesis of the formation of NAFTLD...
Non-alcoholic fatty liver disease, pathogenesis, steatosis, steatohepatitis
Короткий адрес: https://sciup.org/14114932
IDR: 14114932 | DOI: 10.5281/zenodo.2256509
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