Normalizing influence of felodipine on arterial pressure daily profile indices

The aim of our work was studying influence of calcium antagonist felodipine on the blood pressure (BP) daily index (DI) in patients with arterial hypertension. 24-h BP monitoring was performed at 29 patients with essential hypertension initially and after 1, 2, 3 and 6 months of felodipine therapy in a dose of 2,5-15 mg per day. Significant reduction of the office BP and 24-h monitoring BP was noted. Favourable influence of felodipine on DI in patients with DI abnormalities was revealed as well. The revealed peculiarities of felodipine allow to recommend it for preventive maintenance of cardiovascular complications in patients with DI complications.