On the interaction of 6-fluoro-3-hydroxypyrazine-2-carboxamide (favipiravir) with arynes
Автор: Zavyalova V.V., Slovesnova N.V., Petrova V.E., Petrov A.Yu., Vatolina S.E., Krinochkin A.P., Kovalev I.S., Shabunina O.V., Kopchuk D.S., Zyryanov G.V.
Журнал: Вестник Южно-Уральского государственного университета. Серия: Химия @vestnik-susu-chemistry
Рубрика: Органическая химия
Статья в выпуске: 4 т.16, 2024 года.
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6-Fluoro-3-hydroxypyrazine-2-carboxamide (favipiravir) was one of the drugs recommended for the treatment of COVID-19. As with other drugs, the issue of disposal of expired medicinal substances is relevant for favipiravir. In the present study we investigated a method for possible chemical utilization of favipiravir by its reaction with arynes (1,2-dehydrobenzenes) to form isoquinolines, usable in practice.
Covid-19, 6-fluoro-3-hydroxypyrazine-2-carboxamide, favipiravir, utilization, arynes, 3-fluoroisoquinoline-1 -carboxamide
Короткий адрес: https://sciup.org/147246056
IDR: 147246056 | DOI: 10.14529/chem240412
