General principles for creating a comprehensive means for the prevention and treatment of osteodystrophic diseases in cattle
Автор: Semenenko M.P., Sampiev A.M., Semenenko K.A., Vinokurova D.P., Abramov A.A.
Статья в выпуске: 4 т.260, 2024 года.
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Osteodystrophy in cattle is a significant problem for the livestock industry, leading to serious disorders of the skeletal system, functions of the musculoskeletal system. However, the range of drugs for the treatment of osteodystrophy is extremely limited. In this regard, it seemed appropriate to develop a complex drug that effectively and simultaneously affects the main key pathological links. Given the limited theoretical basis and practical platform for such developments, at the first stage of drug design of an osteotropic drug, it seemed methodologically useful to formulate general principles for its design, which was the purpose of the presented study. Using the proposed methodological approach, pharmacotherapeutic groups were determined, desirable to include in its composition. These are sources of bioavailable calcium, vitamins C, D, K, osteotropic macro- and microelements.
Cattle, osteodystrophy, phosphorus-calcium metabolism, hypovitaminosis, general principles of drug design, osteotropic agents
Короткий адрес: https://sciup.org/142242900
IDR: 142242900 | DOI: 10.31588/2413_4201_1883_4_260_237