Effectiveness assessment of vaccines and disinfectants against cow clostridiosis at the Republic of Bashkortostan dairy complexes

The purpose of the study is to evaluate the preventive effectiveness of the use of modern veterinary vaccines (One Shot Ultra 8, TOXIPRA Plus, Koglavax and Pastanarm 8) and the disinfectant Forbicida in comparison with hydrogen peroxide against clostridiosis of dairy cows, carried out in conditions of large dairy complexes of the Republic of Bashkortostan. Analyzes of biomaterial (internal organs and blood serum) of cows were carried out at the testing center of the State Budgetary Institution “Bashkir Research and Production Veterinary Laboratory” in compliance with regulated methods and in accordance with approved regulatory documents - international standards (GOST) and technical specifications (TU). Based on the laboratory tests carried out, we can conclude that without objective identification of the species of anaerobic bacteria clostridia, uncontrolled vaccination of livestock does not provide the necessary level of protection of the body of dairy cattle from this disease. According to the obtained microscopic studies of pathological materials, the most common cultures of clostridia cells are the species of perfringens (C. perfringens) and chauvoei (C. chauvoei), the latter of which is the causative agent of livestock emkara. In this regard, to maintain the required level of specific immunity protection of cows, monthly monitoring of antibodies to toxins remains, the level of which should be at least 40 % inhibition. However, the high effectiveness of specific prevention of clostridia is not achieved by any of the listed vaccines, which requires mandatory monitoring of the level of inhibition of antibodies in blood serum to identified types of clostridia and the introduction of strict sanitary treatment of livestock areas with disinfectant solutions. The use of a 10 % solution of Forbicida or 6 % hydrogen peroxide with an exposure of 24 and 3 hours, respectively, ensures 100 % death of pathogenic bacteria of the 3rd-4th group.