Assessing morphofunctional state of microcirculation channel in smoking young males

According to statistical data provided by the World Health Organization, death causes related to smoking annually account for approximately six million deaths all over the world, and here more than five million deaths are directly caused by smoking and more than 600 hundred thousand deaths occur due to passive smoking. In order to study effects produced by smoking on human microcirculation, we examined capillary blood flow and morphofunctional state of capillaries in smoking and non-smoking people. 195 practically healthy young males aged 17-21 took part in our research; at that moment they were studying at the North-East State University. Microcirculation parameters were examined with non-invasive techniques, namely via computer capillaroscopy performed in a zone of skin swelling near the nail-bed. We obtained 12 quantitative parameters to characterize the microcirculation channel. Having analyzed the data, we revealed a shift in artery-venous ratio of a capillary dimensions towards a greater diameter of an artery section and smaller diameter of a venous section in a capillary among smoking young males; there was also a decrease in capillary length...