Our experience in application of hexane extract of Serenoa repens (permixon) extract in case of chronic prostatitis

Benign prostatic hyperplasia (BPH) is a common disease among older men, which has a strong effect on their quality of life causing lower urinary tract symptoms (LUTS). Recently, special attention has been paid to the pathogenetic role of chronic inflammation in the pathogenesis of BPH. In connection with this, researchers continue the search for drugs with anti-inflammatory action and suitable for long-term use. Permixon is a hexane lipidosterol extract of Serenoa repens, consisting of a mixture of free and esterified long chain fatty acids, polyprenes and phytosterols. It has specificity and selectivity towards the prostate, and also has a wide range of biological activity due to the large number of ingredients. The Permixon main mechanisms of action are its anti-androgenic (inhibition of 5а-reductase activity), pro-apoptotic, anti-proliferative and anti-inflammatory properties. Permixon has no effect on the production of prostate-specific antigen and does not cause side effects...