Peculiarities of basal and stimulated secretion of interleukine 2 and 4 by mononuclear blood cells in autoimmune diabetes

Автор: Saprina T.V., Lazarenko F.E., Prokhorenko T.S., Stolyarova V.A., Ryazantseva N.V.

Журнал: Сибирский журнал клинической и экспериментальной медицины @cardiotomsk

Рубрика: Клинические исследования

Статья в выпуске: 1 т.25, 2010 года.

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The aim of the study was to evaluate the basal and phytoagglutinin stimulated production of interleukins 2 (IL 2) and 4 (IL 4) by mononuclear leukocytes in diabetes mellitus. 8 patients with type 1 diabetes, 21 patients with type 2 diabetes and 6 patients with latent autoimmune diabetes in adults (LADA) were included in cross sectional research. In type 1 diabetes basal production of IL 2 is increased, and basal production of IL 4 is decreased. It is of interest that production of IL 4 in LADA was significantly higher.

Autoimmune diabetes mellitus, type 1 diabetes mellitus, latent autoimmune diabetes in adults, cytokine production by mononuclear leukocytes, interleukin 2, interleukin 4

Короткий адрес: https://sciup.org/14919189

IDR: 14919189

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