The long-term efficacy of an ablation procedure in patients with low lv ejection fraction and ventricular tachyarrhythmias originated from right ventricular outflow tract

The aim of this prospective observational study was to assess efficacy and safety of the ablation procedure in patients with low LV ejection fraction (LVEF) and ventricular tachyarrhythmias originated from right ventricular outflow tract (RVOT) during long-term follow up. Fifty four consecutive patients with symptomatic premature ventricular complexes (PVC) or ventricular tachycardias (VT) with left bundle branch block (LBBB) pattern, inferior axis morphology and transition zone predominantly in V3-V4 were included in this study. The patients were followed up during 36 months after ablation procedure. The mean follow up period was 42.2±6 months. The long-term efficacy after one ablation procedure was 94.4% (51 patients) and after redo procedures - 98.1 % (53 patients). The LVEF increased from 42±2 at baseline to 56±5% after 36 months of follow up (p = 0.001). Radiofrequency catheter ablation in patients with low LVEF and ventricular tachyarrhythmias originated from RVOT is a safe and highly effective treatment during long-term follow up.