Peculiarities of influence made by diabetes mellitus as comorbid pathology on the system of sex hormones and their receptors in tumors of different histological origin
Автор: Frantsiyants E.M., Surikova E.I., Bandovkina V.A., Kaplieva I.V., Pogorelova Yu.A., Neskubina I.V., Cheryarina N.D., Trepitaki L.K., Morozova M.I., Kotieva I.M., Shatova Yu.S.
Журнал: Cardiometry @cardiometry
Статья в выпуске: 24, 2022 года.
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Improving the survival of cancer patients contributes to a growing number of patients with chronic comorbidities, including diabetes mellitus (DM). Moreover, higher risk of cancer development in patients with DM and poor prognosis determine the importance of studying the mechanisms mediating the effect of altered glucose metabolism made on the growth and metastasis of malignant tumors [3,4]. The polyetiology of both pathologies and the presence of research studies that do not confirm a direct relationship between DM and the development of malignant neoplasms indicate the complex nature of their relationship with the possible context-dependent regulation of many cellular processes associated with carcinogenesis and the development of DM [1,2]. An important role in the processes of the regulation is played by an imbalance in the system of sex hormones.
Короткий адрес: https://sciup.org/148326321
IDR: 148326321 | DOI: 10.18137/cardiometry.2022.24.conf.28
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