Polymorphisms of xenobiotic metabolism enzyme genes CYP2E1, GSTM1, GSTT1, EPHX1 as biomarkers of sensitivity to exposure to water disinfection byproducts (using chloroform as an example)
Автор: Drozdova E.V., Kolesneva E.V., Syakhovich V.E., Dalhina N.A.
Журнал: Анализ риска здоровью @journal-fcrisk
Рубрика: Медико-биологические аспекты оценки воздействия факторов риска
Статья в выпуске: 1 (41), 2023 года.
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Chloroform accumulation in the body and the increase in its steady-state concentrations in blood of exposed people have been established to be associated with polymorphisms of enzyme genes in a genotype involved in metabolism of water disinfection byproducts (A415G of EPHX1 gene, C1091T of CYP2E1 gene, zero mutations of GSTT1 and GSTM1 genes) (p
Cyp2e1, gstm1, gstt1, ephx1 genes, disinfection byproducts, drinking water, gene polymorphism, biomonitoring, health risk assessment, biomarkers of susceptibility
Короткий адрес: https://sciup.org/142237421
IDR: 142237421 | DOI: 10.21668/health.risk/2023.1.15
