Compliance with drug therapy in patients with coronary artery disease undergoing coronary artery bypass grafting

Purpose of the study was to evaluate the dynamics of perioperative compliance with drug therapy in patients who underwent coronary artery bypass grafting (CABG). A total of 320 patients with stable coronary artery disease (CAD), who underwent CABG, were included in the study. Patients’ medical conditions were evaluated; data from patients’ medical records and out-patient medical records were used to analyze the results of the laboratory and instrumental tests. The patients filled a questionnaire reflecting social and demographic data and received therapy before CABG and within one year after surgery. The study found a decrease in the number of patients with the elevated cholesterol levels one year after surgery. However, the target values of total cholesterol (TC) and/or low density lipoproteins (LDL) were achieved in 48% of patients. The number of patients, who achieved compensation to hypertension one year after CABG, did not significantly change. Extremely low compliance with drug therapy in patients before surgery was found. Less than half of patients received antiplatelet medications, ß-blockers (BB), and angiotensin-converting enzyme (ACE) inhibitors; only 25% of patients were taking statins. One year after CABG, a significant increase in the number of patients receiving the appropriate drug group was reported. However, only half of patients, who underwent surgery, achieved the main goals of secondary prevention.