The problem of heart transplant rejection and ways of optimizing the assessment of endomyocardial biopsy results
Автор: Stavenchuk T.V., Kosmachova E.D., Shelestova I.A., Slavinsky A.A., Terman E.A., Verevkin A.A., Medvedeva L.A., Barbuhatty K.O., Tatarintseva Z.G., Porchanov V.A.
Журнал: Клиническая практика @clinpractice
Рубрика: Оригинальные исследования
Статья в выпуске: 3 (31), 2017 года.
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The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%).
Computerised morphometric study, endomyocardial biopsy, heart transplant rejection
Короткий адрес: https://sciup.org/143164645
IDR: 143164645
