Problematic aspects of polypragmasia in the development of multimorbidity in elderly and senile patients
Автор: Davudov Radzhab K., Glukhova Sofia A., Misikov Zarina G., Vishnyakova Victoria O., Dudchenko Ekaterina S., Yarkov Vladislav N.
Журнал: Cardiometry @cardiometry
Рубрика: Original research
Статья в выпуске: 25, 2022 года.
Бесплатный доступ
It is known that is an ambiguous phenomenon in medicine. There is no generally accepted definition of the concept, and approaches to the interpretation of the essence of the category in question are also different, since polypragmasia, being vital for certain diseases, can become extremely dangerous in certain conditions of the human body, as well as negatively affect the health of patients of certain age groups. In particular, elderly and senile patients, often in a state of comorbidity or polymorbidity and taking a significant amount of medications (both prescribed by a doctor and without one), are at risk of a possible deterioration in their health. Accordingly, the identification of problematic aspects of polypragmasia in the development of comorbidity in elderly and senile patients, as well as the identification of ways to reduce the negative impact on the state of health of extended drug therapy is quite relevant in modern conditions.
Polypragmasia, comorbidity, consequences, elderly and senile age, medication, problematic aspect
Короткий адрес: https://sciup.org/148326589
IDR: 148326589 | DOI: 10.18137/cardiometry.2022.25.1924
Список литературы Problematic aspects of polypragmasia in the development of multimorbidity in elderly and senile patients
- Pazan F., Kater J., Wehling M. A systematic review and a new classification of list-making tools for improving the medical treatment of the elderly. Eur J Clin Pharmacol. 2019; 75 (5): 619–625
- Bir S. et al. Qualitative drug use and health outcomes among older men living in the community: an observational study. Br J Klin Pharmacol. 2011; 71 (4): 592-599
- Fulton M.M., Allen E.R. Polypragmasia in the elderly: a literature review. Nurse Practice J Am Acad. 2005; 17 (4):123-132
- Shenoy P., Harugeri A. Participation of elderly patients in clinical trials. Perspekt Klin Res. 2015; 6 (4): 184-189
- National Institute of Health and Excellence (NICE): Multimorbidity: Clinical Assessment and Treatment. (as of October 27, 2020)] ; 2016 Available online: https://www.nice.org.uk/guidance/ng56
- Fortin M., La pointe L., Hudson C., Vanessa A., Netu AL, Maltais D. Multimorbidity and quality of life in primary health care: a systematic review. The quality of health. The results of life. 2004; р.12-25
- Nunes BP, Flores TR, Mielke GI, Thumb E., Facchini LA Multimorbidity and mortality in the elderly: a systematic review and meta-analysis. Arch Gerontol. Geriatrician. 2016; 67: 130-138.
- Guthrie B., Pine K., Alderson P., McMurdo M.E., Mercer S.V. Adaptation of clinical guidelines taking into account multimorbidity. BMJ. 2012; 345:e63411
- Lavaan A.H. Galllacher P.F. O’mahoney D. Theы method halvedя quantities oshibok at the appointed physician in the fireы patient with mullerь. wedge. Interv. Old age. 2016; 11:857–866.
- Morin, L., Johnell, K., Laroche, M.L., Fastbom, J., and Vastesson, J.V. (2018). Epidemiology of polypragmasia in the elderly: a prospective cohort study based on registers. wedge. Epidemiol. 10, 289-298.
- Pereira K.G., Peres M.A., Iop D., Boeing A.S., Boeing A.F., Aziz M. et al. (2017). Polypragmasia among the elderly: a population study. The Reverend Brass Epidemiol. 20 (2), 335-344
- Eurostat (2021). People in the EU: who are we and how do we live? Luxembourg, Publishing Office of the European Union
- Rutledge P.Ah. O’mahoney.S. Woodhouse C.V. He complained about drug reactions to the patient. no. J. Wedge. farm. 2004.; 57: 121–126
- Jorgensen T.L. et al. Polypragmasia and drug use in elderly cancer patients in Denmark in the period from 1996 to 2006. J Geriatr Oncol. 2012; 3 (1):33-40
- Mangoni A.A., Jackson S.H. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Klin Pharmacol. 2004; 57 (1): 6-14.
- Lilakanok N. et al. The relationship between polypragmasia and death: a systematic review and meta-analysis. J Am Pharm Association. 2017; 57 (6): 729–738.
- Wastesson JW, et al. Updated information on the clinical consequences of polypragmasia in the elderly: a descriptive review. Expert opinion of Drug Safe. 2018; 17 (12): 1185–1196
- Niikawa H. and co-author. The relationship between polypragmasia and cognitive impairment in elderly Japanese living in urban environments. Geriatr Gerontol Int. 2017; 17 (9): 1286–1293
- Katsimpris A. et al. The relationship between polypragmasia and physical function in the elderly: a systematic review. J Gen Intern Med. 2019; 34 (9): 1865–1873
- Cullinan S., Rage HC, Byrne S., O’Mahony D., Kearney P., Sum L. Problems of cancellation of appointments in a multimorbid patient. Euro. J. Hospice Farm. 2017; 24:43-46.
- Ouellet GM, Ouellet JA, Ti net tiME The principle of rational appointment and cancellation of appointment in elderly people with multiple chronic diseases.ter. Dop. Preparation of Sap. 2018; 9: 639-652
