Prevention and therapy of metabolic disorders of new-bodied highly productive cows

The aim of this work was to normalize the metabolism of highly productive new-bodied cows with new biopreparations PS-2, Prevention-N-E and PDE (denatured emulsified placenta) with E-selenium, as well as therapy of subclinical ketosis with an energy drink. The research work was carried out on Holstein cows of black-and-white breed, 2-3 lactation, average milk yield of 9000 kg. We selected 4 groups of deep-bed cows according to the principle of analog groups and performed injections of biological preparations 40, 20 and 10 days before calving. Biologics PS-2 and Prevention-N-E have a corrective effect on the synthesis of aminotransferases, mineral and carbohydrate metabolism, the digestibility of macronutrients, against which the number of new-bodied cows with latent ketosis is reduced by 2 times. For ketosis therapy, an energy drink consisting of propylene glycol, soda, salt, cellobacterin, molasses is proposed. For this series of experiments, 2 experimental and control groups of new-bodied cows with a BHB (beta-hydroxybutyrate) level of 1.1-3.0 mmol/l were formed. The 1st experimental group was injected with 40% glucose and the drug Hepatoject, the 2nd experimental group was given an energy drink. After treatment in the 2nd experimental group, the average BHB was 1.1 mmol/l, but in the 1st experimental group it was higher than normal and equal to 1.5 mmol/l. The daily dose, the average fat and protein content, and the fat/protein ratio were within the normal range at the final stage of the studies. Based on the results obtained, it should be concluded that latent ketosis is a fairly common pathology and affects to a greater extent new-bodied highly productive cows, while not showing symptoms, causing significant economic damage. That is why, for the prevention of ketosis, we recommend Prevention-N-E, PS-2 drugs, and for the treatment of detected cases, drinking an energy drink.