Prediction of respiratory complications after lung resection

The aim of the study is to examine the frequency and structure of respiratory complications after lung resection, and factors influencing their development. Materials and Methods. The study was conducted at the department of thoracic surgical oncology, Ulyanovsk Regional Oncological Clinical Hospital. The analysis included data from 468 patients who underwent lobectomy or atypical resection for neoplasms using anterolateral thoracotomy (January 01, 2021 – December 31, 2023). Results. The incidence of respiratory complications in the postoperative period was 19.02 %. Univariate analysis revealed that smoking history, peak flow rate (PFR), predicted postoperative forced expiratory volume in 1 second (pFOFEV1), surgery and lobectomy duration were significant factors for predicting the risks of respiratory complications. With a 1 % increase in PFR, the likelihood of respiratory complications decreased by 1.080 times (OR=1.080 (95 % CI 1.034–1.127)). The chronic obstructive pulmonary disease (COPD) increased the risks of complications: in GOLD2 by 16.392 times (OR=16.392 (95 % CI 2.686– 100.083), in GOLD3 by 35.082 times (OR=35.082 (95 % CI 1.267–970.683). After lobectomy, the probability of complications increased by 3.251 times (OR=0.308 (95 % CI 0.105–0.899), p=0.031). Conclusion. The study results showed that the incidence of postoperative respiratory complications was 19.02 %. Significant predictors of complications are COPD (GOLD 2 and GOLD 3), PFR, and lobectomy.