Psychological predictors of addiction associated HIV-infection accelerating progress

Multiple psycho-emotional disorders are associated with drug abuse, and they can also be a therapeutic target in the selection and conduction of psychotherapy. Disturbance of neuroimmune interactions, that is typical for drug addiction, is also an essential link in the pathogenesis of AIDS, and can serve as a factor that contributes to accelerated progression of HIV infection among drug addicts. The work is devoted to investigation of HIV-infection accelerated progress psychological risk factors among intravenous drug abusers. As experimental psychodiagnostic technique we chose Szondi test. The ten years clinical catamnesis data were analyzed. Data reduction was carried out by means of factor analysis and exponential regression. Szondi test revealed multicomponent factor, reliably positively associated with HIV-infection accelerating progress (10 years survival, CD4+-lymphocytes absolute concentration decrease rate). This allows on the basis of the analysis of the general psychodynamics of the individual and the external manifestations of the deep structures of the psyche of drug abusers to predict the risk of accelerated progress of HIV infection, and can serve as one of the reasons, as well as clinical indications, for development and implementation of personalized therapy