Rabies: historical information and world distribution area

Rabies virus is neurotropic (collects in nerve cells) and mainly infects the central nervous system. In the body of sick animals, the virus is mainly located in the gray matter of the brain and multiplies there, accumulates during the disease and remains in the body for a long time (up to 3 months) after the animal dies, where it is not neutralized. The most virulent virus is isolated from wolves and dogs, and the less virulent ones are isolated from horses, bulls, sheep and humans. In addition to the nervous system, the virus is found in saliva and salivary glands, lacrimal glands, internal organs, urine, and in the early stages of the disease, in the blood. The development of the virus in the body also depends on the amount of the virus, the localization of the bite and its virulence. The incubation period of the disease is reduced, especially when the organs close to the brain are bitten - face, head, neck.