Synaptoarchitectonics reorganization of the sensorimotor cortex in rats of Krushinsky-Molodkina line after a single soundimpact exceeding maximum acceptable level

We studied the effects of a single sound exposure (SSE) maximum permissible level on synapses in layer I of the rats sensorimotor cortex (n = 90, Krushinsky-Molodkina line). Used methods of electron microscopy, morphometric and statistical analysis. After the SNE of synapses total numerical density was significantly reduced and after 4, 8 and 24 h, respectively 67.7; 95.0 and 51.4 % of the control. In addition, changed the relative content of small, medium and large synapses, synapses with different height of dense projections, flat, (+) and () curved contacts, changed the shape and size of spines. All this testified to a significant reorganization of the experimental animals cerebral cortex synaptoarchitectonics after the SSE. All this can be structural basis of psycho-biosocial and neurological manifestations of the impact of the noise exceeding the maximum value, as well as basis for the formation of pathological brain systems based on the hyperactive neurons and brain neural networks.