Retrospective estimation of the dynamics of asthenic syndrome development in exposed residents of settlements in the Techa river basin

In persons exposed to radiation, both in the early period and in the more distant periods of observation, asthenic syndrome is detected with a high frequency due to the action of radiation and related non-radiation factors. Background. The widespread use of atomic energy in the national economy, the prospects for long-range space flights determine the need to study the effect of radiation on the state of the central nervous system and the development of asthenic syndrome in certain social and professional groups of the population. Objective. Retrospective estimation of the dynamics of the development of asthenic syndrome in residents of the settlements of the Techa river basin exposed to ionizing radiation. Materials and Methods. Using the data of the archival case histories and outpatient records of patients observed in the clinical department of the USPC RM in the period from 1950 to 2005, two study groups were formed, depending on the accumulated radiation dose. The first group included 100 patients whose cumulative radiation dose exceeded 1 gray. The second group consisted of 80 patients with an accumulated radiation dose of no more than 0.5 Gy. The total follow-up was divided into 11 periods of 5 years each. In each time interval, clinical data (neurologist, therapist, psychiatrist), laboratory and instrumental (EEG) studies were assessed. Statistical processing of the results was performed using the Statistica (Ver. 7.0) and MS Excel software package, using Student's t test, Pearson’s x2 test, and Mann-Whitney U test. Differences were considered significant at p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }