Results of cell cycle analysis in bladder cancer

Bladder Cancer (BC) is a fairly frequent pathology: its occurrence is about 2-5% of all neoplasms, and 30-40% of tumors of the urinary system; ranks second after prostate cancer. With the advent of flow cytometry method has been possible to quickly and objectively identify particular proliferation and reliably identify abnormal content of DNA in the nuclei of tumor cells and to study the correlation ties with the classical parameters characterizing the tumor during the process. Results were analyzed urine flow cytometry sludge RMP 50 patients (10 women and 40 men). It identified the dominance of the high degree of malignancy in combination tumors: T3-T4 level invasion and the high grade neoplasms (G3) were noted in 83.33% of cases, with diploid tumors T3-T4 level of invasion and G3 BC malignancy met in 16.67% cases. Proliferative activity of transitional cell bladder epithelium in malignant lesions greater than normal value in 7-8 times.