Риски лучевой терапии для детей и подростков. Обзор литературы

Риски лучевой терапии для детей и подростков. Обзор литературы

Автор: Щербенко О.И.

Журнал: Вестник Российского научного центра рентгенорадиологии Минздрава России @vestnik-rncrr

Рубрика: Обзор

Статья в выпуске: 1 т.24, 2024 года.

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Начиная с 50-х годов 20 века, лучевая терапия активно применяется при лечении опухолей у детей. По мере накопления клинических наблюдений стало ясно, что при высокой непосредственной эффективности метода его отдаленные результаты могут нивелироваться за счет развития отдаленных последствий. Как выяснилось, вероятность развития тяжелых и даже инвалидизирующих последствий зависит от возраста ребенка в момент лечения, величин разовых и суммарных доз, объемов облучения. С развитием технических средств лучевой терапии, созданием новых противоопухолевых препаратов стало возможным в ряде ситуаций отказаться от применения лучевой терапии, уменьшать дозы и объемы облучения, однако полностью исключить радиационное воздействие на критические структуры удается далеко не всегда. Поэтому представилось целесообразным провести анализ имеющейся в литературе информации о возможных последствиях радиационного воздействия на различные органы и системы у детей. Знание этих рисков должно позволить врачам, осуществляющим лечение и динамический мониторинг за детьми, получавшими лучевую терапию, предупреждать и своевременно выявлять развитие возможных радиационных повреждений.

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Опухоли у детей, лучевая терапия, отдаленные последствия

Короткий адрес: https://sciup.org/149145024

IDR: 149145024

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