Sesquiterpene lactons of the genus Artemisia L

Sesquiterpene lactones are of particular interest to researchers around the world in connection with a wide range of their pharmacological activity - antimalarial, antitumor, anthelmintic, cardiotonic, anti-inflammatory, analgesic, etc. The genus Artemisia L. (Wormwood) is one of the genus characterized by the greatest variety of lactones. Artemisia L. is one of the largest and most perfect genus of the Asteraceae ( Compositae ). This genus includes more than 500 species, 174 species are found in the Russian Federation and the CIS countries, 76 species grow in Siberia and 46 species are found in Buryatia. Guaianelactones (absintin, anabsintin, artabsin, etc.) were found in plants of the subgenus Artemisia of the subsection Absinthium ( A. absinthium, A. sieversiana, A. pontica ). These compounds are the precursors of bicyclic sesquiterpenoid essential oils - chamazulene, which has anti-inflammatory effects.