The content of non-esterified fatty acids and some adipokines in the blood serum in patients with the first episode of schizophrenia and the nature of their changes during antipsychotic therapy

Introduction. According to various authors, the prevalence of metabolic syndrome among patients with schizophrenia was 27-67%. Metabolic syndrome was pathogenetically related to cardiovascular pathology, which was the leading cause of death in patients with schizophrenia. At the same time, the increased content of non-esterified fatty acids in the blood serum and aberrant production of adipokines were important in the mechanisms of the development of metabolic syndrome.