The partial functions of kidneys in type 1 diabetes mellitus in patients with different types of anemia

Aim: studying of partial functions in type 1 diabetes patients (MD 1) with different types of anemia. Materials and methods: 93 patients with MD 1 anemia are surveyed: 29 with anemia of chronic diseases (ACD), 51 with iron deficiency anemia (IDA). Comparison group - 28 MD 1 patients without anemia. To estimate the function of kidneys we calculated glomerular filtration rate and examined the level of a daily egestion of microalbumin with urine, tubular reabsorption of water, daily egestion of nitrogen of amino acids, daily egestion of ammonia with urine. Results: glomerular filtration rate and a tubular reabsorption of water is lowered at MD 1 patients with anemia and without. Glomerular filtration rate at MD 1 patients with ACD is lower as compared to MD 1 patients with IDA and without anemia. MD 1 patients with ACD have increased level of egestion of nitrogen of amino acids, thus correlation communication with glomerular filtration rate is absent. Conclusion: thus, MD 1 patients with ACD have a lesion of the glomerular apparatus of the kidneys, shown by lower glomerular filtration rate, than in MD 1 patients without anemia and MD 1 patients with IDA. Also MD 1 patients with ACD have defect signs of luminal membranes of cells of proximal department of tubular of kidneys which are absent in MD 1 patients without anemia and with IDA.