Enhancement of freshmen's adaptation to high school

Aim. The article deals with studying the effect of a complex selenium-containing compound and physio disease-preventing means on the enhancement of biochemical indicators in freshmen living in a selenium-deficient area. Materials and methods. We conducted 12 longitudinal studies with the students of the first and second year studying at Chuvash Universities (n = 180). Selenium concentration in blood serum was established with the help of fluorometry performed according to Golubkina’s interpretation (Fluorat-02-2M). The activity of lipid peroxidation (c.u.) and antioxidant system (c.u.) was studied using induced chemiluminescence (Biochemiluminometer БХЛ-06). Results. The use of Selenes+ together with a disease-preventing photochrome session is accompanied by antioxidant, metabolic, and hemopoietic effects manifested in the increase of antioxidant activity and selenium concentration by 31.1 and 62.5 %, respectively, and the decrease of lipid peroxidation by 4.1-19.7 % compared to control values. The use of Selenes+ together with exercises contributes to less pronounced stress in the cardiovascular system both during the study and exam periods. Conclusion. Therefore, selenium correction of body adaptation with respect to a biogeochemical specifics of a region normalizes the balance between prooxidant and antioxidant elements of the antioxidant protection system and provides an accelerated shift from short-term to long-term adaptation.