Современные подходы к диагностике и лечению билиарных осложнений после трансплантации печени. Обзор литературы

Автор: Магомедов К. М., Новрузбеков М. С., Гуляев В. А., Луцык К. Н., Казымов Б. И., Алекберов К. Ф., Ахмедов А. Р., Аносова Е. Ю., Яремин Б. И.

Журнал: Вестник медицинского института "РЕАВИЗ": реабилитация, врач и здоровье @vestnik-reaviz

Рубрика: Донорство и трансплантация органов и тканей

Статья в выпуске: 6 т.13, 2023 года.

Бесплатный доступ

Актуальность. Выбор билиарного анастомоза является основным фактором, определяющим риск развития билиарных осложнений после ортотопической трансплантации печени. Двумя наиболее распространёнными формами реконструкции желчевыводящих путей являются холедохохоледохостомия (анастомоз протока с протоком) и холедохоеюностомия (соединение желчного протока с частью тощей кишки). Выбор реконструкции желчевыводящих путей определяется множеством факторов, включая основную патологию печени, размер желчных протоков донора и реципиента, предшествующую трансплантацию или предыдущую операцию на желчевыводящих путях, а также предпочтения выполняющего операцию хирурга. Несмотря на верно подобранный способ реконструкции нечасто, но возникают осложнения, такие как стриктуры, литиаз, билома, подтекание желчи.Цель: представить обзор литературы по способам диагностики и лечения билиарных осложнений после трансплантации печени.Материалы и методы. Проведён анализ литературных источников на английском и русском языках с 2010 по 2023 год по данной теме в базах PubMed, MEDLINE, Google Scholar. В обзоре освещены клинические исследования, а также литературные обзоры по схожей тематике с акцентом на лечение и диагностику билиарных осложнений.Заключение. Проблема билиарных осложнений трансплантации печени остается актуальной и до конца нерешенной. Неинвазивные методы визуализации осложнений, возникающих после операций на желчевыводящих путях, имеют перспективы развития. Тактика перкутанных, эндоскопических и открытых вмешательств на билиарном дереве трансплантата требует дальнейшего совершенствования.

Еще

Билиарные осложнения, трансплантация печени, эндоскопическая ретроградная холангиопанкреатография, билиарное дренирование

Короткий адрес: https://sciup.org/143181099

IDR: 143181099 | DOI: 10.20340/vmi-rvz.2023.6.TX.1

Список литературы Современные подходы к диагностике и лечению билиарных осложнений после трансплантации печени. Обзор литературы

Arslan MF, Haliloglu N, Erden A. MR cholangiopancreatography findings of biliary tract complications after liver transplantation. Turk J Med Sci. 2018 Oct 31;48(5):1006-1012. https://doi.org/10.3906/sag-1803-68; PMID: 30384568.
Woo HY, Lee IS, Chang JH, Youn SB, Bae SH, Choi JY, Chun HJ, You YK, Kim DG, Yoon SK. Outcome of donor biliary complications following living donor liver transplantation. Korean J Intern Med. 2018 Jul;33(4):705-715. https://doi.org/10.3904/kjim.2017.264; Epub 2018 Mar 14. PMID: 29529841; PMCID: PMC6030404.
Wojcicki M, Milkiewicz P, Silva M. Biliary tract complications after liver transplantation: a review. Dig Surg. 2008;25(4):245-57. https://doi.org/10.1159/000144653; Epub 2008 Jul 15. PMID: 18628624.
Rao HB, Prakash A, Sudhindran S, Venu RP. Biliary strictures complicating living donor liver transplantation: Problems, novel insights and solutions. World J Gastroenterol. 2018 May 21;24(19):2061-2072. https://doi.org/10.3748/wjg.v24.i19.2061; PMID: 29785075; PMCID: PMC5960812.
López Álvarez M, Otero A, Vázquez Millán MA, Suárez López F, Alonso Aguirre P. Endoscopic treatment of biliary complications after liver transplantation. Rev Esp Enferm Dig. 2020 Aug;112(8):605-608. https://doi.org/10.17235/reed.2020.6704/2019. PMID: 32543875.
Олисов О.Д. Билиарные осложнения после ортотопической трансплантации печени. Трансплантология. 2009;(2):44-50. https://doi.org/10.23873/2074-0506-2009-0-2-44-50 [Olisov O.D. Biliary complications after orthotopic liver transplantation. Transplantation. 2009;(2):44-50. https://doi.org/10.23873/2074-0506-2009-0-2-44-50 (In Russ)].
Elkomos BE, Abdelaal A. Do We Need to Use a Stent in Biliary Reconstruction to Decrease the Incidence of Biliary Complications in Liver Transplantation? A Systematic Review and Meta-Analysis. J Gastrointest Surg. 2023 Jan;27(1):180-196. https://doi.org/10.1007/s11605-022-05479-7; Epub 2022 Nov 14. PMID: 36376727; PMCID: PMC9877101.
Gastaca M. Biliary complications after orthotopic liver transplantation: a review of incidence and risk factors. TransplantProc. 2012 Jul-Aug;44(6):1545-9. https://doi.org/10.1016/j.transproceed.2012.05.008; PMID: 22841209.
Yoon YC, Etesami K, Kaur N, Emamaullee J, Kim J, Zielsdorf S, Ahearn A, Sher L, Genyk Y, Kwon YK. Biliary Internal Stents and Biliary Complications in Adult Liver Transplantation. Transplant Proc. 2021 Jan-Feb;53(1):171-176. https://doi.org/10.1016/j.transproceed.2020.06.019; Epub 2020 Jul 17. PMID: 32684369.
Duailibi DF, Ribeiro MA Jr. Biliary complications following deceased and living donor liver transplantation: a review. Transplant Proc. 2010 Mar;42(2):517-20. https://doi.org/10.1016/j.transproceed.2010.01.017; PMID: 20304182.
Seehofer D, Eurich D, Veltzke-Schlieker W, Neuhaus P. Biliary complications after liver transplantation: old problems and new challenges. Am J Transplant. 2013 Feb;13(2):253-65. https://doi.org/10.1111/ajt.12034; Epub 2013 Jan 17. PMID: 23331505.
Buros C, Dave AA, Furlan A. Immediate and Late Complications After Liver Transplantation. Radiol Clin North Am. 2023 Sep;61 (5):785-795. https://doi.org/10.1016Zj.rcl.2023.04.002; Epub 2023 May 16. PMID: 37495287.
Kochhar G, Parungao JM, Hanouneh IA, Parsi MA. Biliary complications following liver transplantation. World J Gastroenterol. 2013 May 21;19(19):2841-6. https://doi.org/10.3748/wjg.v19.i19.2841; PMID: 23704818; PMCID: PMC3660810.
Calne RY. A new technique for biliary drainage in orthotopic liver transplantation using the gallbladder as a pedicle graft conduit between the donor and recipient common bile ducts. Ann Surg. 1976;184:605-609.
Dubbled J, Hoekstra H, Farid W, et al. Similar liver transplantation survival with selected cardiac death donors and brain death donors. Br J Surg. 2010;97:744.
Grief F, Bronsther OL, VanThiel DH, et al. The incidence, timing and management of biliary tract complications after orthotopic liver transplantation. Ann Surg. 1994;219:40-45.
Calne RY, McMaster P, Portmann B, et al. Observations on preservation, bile drainage and rejection in 64 human orthotopic liver allografts. Ann Surg. 1977;186:282.
Balderramo D, Navasa M, Cardenas A. Current management of biliary complications after liver transplantation: emphasis on endoscopic therapy. Gastroenterol Hepatol. 2011;34:107.
Gastaca M. Biliary complications after orthotopic liver transplantation: a review of incidence and risk factors. TransplantProc. 2012;44:1545-1549.
Akamatsu N, Sugawara Y, Hashimoto D. Biliary reconstruction, its complications and management of biliary complications after adult liver transplantation: a systematic review of the incidence, risk factors and outcome. Transpl Int. 2011 ; 24:379.
O'Connor TP, Lewis WD, Jenkins RL. Biliary tract complica- tions after liver transplantation. Arch Surg. 1995;130:312.
Lerut J, Gordon RD, Iwatsuki S, et al. Biliary tract complications in human orthotopic liver transplantation. Transplantation. 1987;43:47-51.
Klien AS, Savader S, Burdick JP, et al. Reduction of morbidity and mortality from biliary complications after liver transplantation. Hepatology. 1991;14:818-823.
Verdonk RC, Buis CI, Porte RJ, et al. Anastomotic biliary stric- tures after liver transplantation: causes and consequences. Liver Transpl. 2006;12:726.
Sundaram V, Jones DT, Shah NH, et al. Posttransplant biliary complications in the pre- and post-model for end-stage liver disease era. Liver Transpl. 2011;17:428.
Kootstra G, Daemen JH, Oomen AP. Categories of non-heartbeating donors. Transplant Proc. 1995;27:2893.
Foley DP, Fernandez LA, Leverson G, et al. Donation after car- diac death. The University of Wisconsin experience with liver transplantation. Ann Surg. 2005;242:724.
De Vera ME, Lopez-Solis R, Dvorchik I, et al. Liver transplantation using donation after cardiac death donors: long-term follow-up from a single center. Am J Transplant. 2009;9:773.
Pine JK, Aldouri A, Young AL, et al. Liver transplantation following donation after cardiac death: an analysis using matched pairs. Liver Transpl. 2009;15:1072.
Suarez F, Otero A, Solla M, et al. Biliary complications after liver transplantation from Maastricht category-2 non-heart-beating donors. Transplantation. 2008;85:9.
Jimenez-Galanes S, Meneu-Diaz JC, Moreno A, et al. Liver transplantation using uncontrolled non-heart-beating donors under normothermic extracorporeal membrane oxygenation. Liver Transpl. 2009;15:1110.
Fondevila C, Hessheimar A, Flores E, et al. Applicability and results of Maastricht type 2 donation after cardiac death liver transplantation. Am J Transplant. 2012;12:162.
Tung BY, Kimmey MB. Biliary complications of orthotopic liver transplantation. Dig Dis. 1999;17:133-144.
Vallera RA, Cotton PB, Clavien PA. Biliary reconstruction for liver transplantation and management of biliary complications: overview and surgery of current practices in the United States. Liver Transpl Surg. 1998;1:143-152.
Sung JY, Costerton JW, Shaffer EA. Defense system in the biliary tract against bacterial infection. Dig Dis Sci. 1992;37:689-696.
Neuhaus P, Blumhardt G, Bechstein WO, et al. Technique and results of biliary reconstruction using side-to-side choledochocholedochostomy in 300 orthotopic liver transplants. Ann Surg. 1994;219:426-434.
Keck H, Langrehr JM, Blumhardt G, et al. Incidence of biliary complications following side-to-side choledochocholedochostomy after liver transplantation. Transplant Proc. 1994;26:3544-3545.
Rabkin JM, Orloff SL, Reed MH, et al. Biliary tract complications of side-to-side without T-tube versus end-to-end with or without T-tube choledochocholedochostomy in liver transplant recipients. Transplantation. 1998;65:193-199.
Davidson BR, Rai R, Kurzawinski TR, et al. Prospective randomized trial of end-to-end versus side-to-side biliary reconstruction after orthotopic liver transplantation. Br J Surg. 1999;86:447-452.
Shaked A. Use of T-tube in liver transplantation. Liver Transpl Surg. 1997;3(suppl):22-23.
Porayko MK, Kondo M, Steers JL. Liver transplantation: late complications of the biliary tract and their management. Semin Liver Dis. 1995;15:139-155.
Sotiropoulos GC, Sgourakis G, Radtke A, et al. Orthotopic liver transplantation: T-tube or not T-tube? Systematic review and meta-analysis of results. Transplantation. 2009;87:1672.
Riediger C, Müller MW, Michalski CW, et al. T-tube or no T-tube in the reconstruction of the biliary tract during orthotopic liver transplantation: systematic review and meta-analysis. Liver Transpl. 2010;16:705.
Weiss S, Schmidt SC, Ulrich F, et al. Biliary reconstruction using a side-to-side choledococholedocostomy with or without T-tube in deceased donor liver transplantation. A prospective randomized trial. Ann Surg. 2009;250:766.
Lopez-Andujar R, Montalva E, Frangi A, et al. T-tube or not T-tube in deceased donor liver transplantation. Preliminary results of a prospective randomized trial. Liver Transpl. 2011;17(suppl 1):79A.
Van Thiel DH, Fagiuoli S, Wright HI, et al. Biliary complications of liver transplantation. Gastrointestinal Endoscopy. 1993;39:455-460.
Bubak ME, Porayko MK, Krom RAF, et al. Complications of liver biopsy in liver transplant patients: Increased sepsis associated with choledochojeju-nostomy. Hepatology. 1991;14:1063-1065.
Galati jS, Monsour Hp, Donovan JP, et al. The nature of complications following liver biopsy in transplant patients with Roux-en-Y choledochojejunos-tomy. Hepatology. 1994;20:651-653.
Reichert PR, Renz JF, Rosenthal P, et al. Biliary complications of reduced-organ liver transplantation. Liver Transpl Surg. 1998;4:343-349.
Emond JC, Whitington PF, Thistlewaite JR, et al. Transplanta- tion of two patients with one liver: analysis of a preliminary expe- rience with "split-liver" grafting. Ann Surg. 1990;212:14-22.
Broelsch CE, Emond JC, Whitington PF, et al. Application of reduced-size liver transplants as split grafts, auxiliary orthotopic grafts and living related segmental transplants. Ann Surg. 1990;214:368-377.
Otte JB. Is it right to develop living related liver transplantation: do reduced and split livers not suffice to cover the needs? Transpl Int. 1995;8:69-73.
De Ville de Goyet J. Split liver transplantation in Europe - 1988 to 1993. Transplantation. 1995;59:1371-1376.
Azoulay D, Astarcioglu I, Bismuth H, et al. Split liver transplantation: the Paul Brousse Policy. Ann Surg. 1996;224:737-748.
Rogiers X, Malago M, Gawad K, et al. One year of experience with extended application and modified techniques of split liver transplantation. Transplantation. 1996;61:1059-1061.

Еще

Статья обзорная