Comparing quality of life and psychological status in patients with rectal cancer after natural orifice specimen extraction surgery (NOSES) versus conventional laparoscopic surgery

Introduction. To evaluate and compare the quality of life and psychological status of patients after laparoscopic surgery for rectal cancer with Natural Orifice Specimen Extraction Surgery (NOSES) and with the conventional laparoscopic. Materials and methods of research. This prospective study included patients at Sechenov University and Harbin medical university. Patients were segregated into NOSES group and CL group based on case-match method. QoL was assessed using the short-form 36 health survey (SF-36), Beck anxiety inventory (BAI), and Spielberger state-trait anxiety inventory (STAI) pre-operation, pre-discharge, postoperative 3 months, and postoperative 6 months. Treatment results. A total of 30 patients (15 in NOSES group and 15 in CL group) were included. At three months postoperatively, role function, physical pain, and emotional state were better in the NOSES group than in the CL group (all p<0.05). At six months postoperatively, NOSES group patients with better than CL group patients in role function, physical function, vitality, social function, emotional state, and mental health (p<0.05). As for postoperative depression, patients in the NOSES group were significantly better than patients in the CL group before discharge (p=0.037) and three months after surgery (p=0.003). In terms of anxiety, patients’ state anxiety in the NOSES group were lower than CL group before discharge (p=0.016), and trait anxiety were better than CL group (p=0.015). Conclusion. This research provides compelling evidence that NOSES offers significant advantages in postoperative QoL, psychological well-being, with comparable surgical outcomes of the CL approach.