Comparative assessment of antibiotic-resistance dynamics of bacteria, isolated from patients with acute and chronic purulent process in orthopaedic-and-traumatiological in-patient department

Antibioticogram analyzing results are shown for S. aureus, S. epidermidis, Enterococcus spp., P. aeruginosa, isolated from patients with chronic osteomyelitis and from open fracture wounds within the period of 2005-2008. The antibiotic resistance of the strains was comparatively assessed using the coefficient of resistance. The analysis demonstrated the tendency towards decreasing of the antibiotic resistance of the strains, isolated from patients with chronic osteomyelitis. The converse results was revealed while studying the antibioticograms of bacteria, isolated from open fracture wounds with increasing resistant isolates in number. Pseudomonas aeruginosa, isolated both from open fracture wounds and osteomyelitis foci, was characterized by high proportion of the strains that were non-sensitive to the antibiotics being tested, though the resistance of this microorganism to antibiotic influence was reliably established to decrease for the period studied.