Comparative evaluation of sorption materials for the removal of trichotecens

Trichothecene mycotoxins (fumonisin B1 and deoxynivalenol) are compounds of the sesquiterpenoid family produced by fungi of the genus Fusarium proliferatum and Fusarium verticillioides. These mycotoxins play a key role in various pathological effects on the cellular systems of the body and the whole organism. The most convenient and effective way to neutralize their effects on the body is to use various sorbents. The aim of our research was to conduct a comparative evaluation of various sorption materials for the removal of trichothecene mycotoxins under in vitro conditions. We have studied the ability of yeast and vegetable β-glucans, lignin (sorbents of plant origin), zeolite, shungite (mineral sorbents) to bind trichothecene mycotoxins fumonisin B1 and deoxynivalenol. The adsorption of these substances was assessed by a method that simulates the conditions of the gastrointestinal tract. As a result of the experiment, it was found that the leaders of sorption to deoxynivalenol are yeast β-glucan (alkaline hydrolysis) sorbing - 94.6 % of mycotoxin, vegetable β-glucan - 91.5 % and shungite - 78.4 %. To mycotoxin fumonisin B1, shungite showed the best sorption - 98.0 %, zeolite - 77.0 % and lignin - 64.8 %. Other sorbents showed themselves to a lesser extent. In general, sorbents of plant origin sorbed deoxynivalenol better, and natural sorbents showed better sorption capacity for fumonisin B1.