Types of iron metabolism disorder in newly diagnosed lymphoma'S patients and during chemotherapy

The iron metabolism disorders, such as iron deficiency anemia or iron overload, can modify the risk of malignancy and promote development more aggressive phenotypes of cancer. To investigate the association between iron metabolism and carcinogenesis we have examined 98 patients suffered from non-Hodgkin's lymphoma. The different types of iron metabolism disorders in newly diagnosed patients are described: 32.6% of patients have cancer-associated high serum ferritin level, 41.7% - the anemia of chronic disease, 14.2% - latent iron deficiency and 2.1% - iron deficiency anemia. During chemotherapy the iron metabolism types' distribution has been changed due to the fraction of patients with chemotherapy-induced anemia (38.8%) has appeared, whereas other types of iron metabolism disorders have been observed less frequently (18.38% of patients have the anemia of chronic disease, 18.4% - cancer-associated high serum ferritin level and 10.2% of patients have latent iron deficiency).