Antiparasitic efficacy of the compound "K-55" at eimeriosis of chickens

Eimeriosis is one of the most common diseases of birds caused by protozoa, which leads to a decrease in productivity and economic losses in poultry farming. In this study, the anti-eimeriosis efficacy of the new compound "K-55" was studied in the treatment of chickens infected with eimeriosis. Under the guidance of teachers of the Department of Epizootology and Parasitology, an experiment was carried out on 30 chickens of twenty-day age who were infected with a titrated dose of sporulated oocysts of eimeria at a dose of 2000 cells per 1 kg of weight. The results of the studies showed that subacute and desquamative catarrhal inflammation was observed in the control groups in the small intestine of chickens experimentally infected with eimeriosis. In some areas of the intestinal wall, the destruction of not only the villi, but also the entire epithelial monolayer of the crypt is noticeable. The hydrographic structure of the small intestine was preserved on the 7th and 14th days after treatment with the K-55 compound. In the intestine there were villi with a flattened and wide base. The prisms in the villi were represented by a multitude of goblet-shaped exocrinoids, with signs of increased secretion. No hypersecretion was detected in the apical zone. The dense base of the villi is characterized by hyperplasia of reticulocytes, fibroblasts and endothelial cells of blood vessels. Apparently, the muscle layer consisted of a continuous and uneven layer. The study showed that the drug "K-55" is effective in the treatment of avian eimeriosis.