Study of the bioactive properties, radical scavenging activity and phenolic profiles of extracts Crocus cancellatus subsp. Mazziaricus (Herb.) B. Mathew, 1982

Study of the bioactive properties, radical scavenging activity and phenolic profiles of extracts Crocus cancellatus subsp. Mazziaricus (Herb.) B. Mathew, 1982

Автор: Deniz Nahide, Aydin Cigdem, Mammadov Ramazan

Журнал: Бюллетень науки и практики @bulletennauki

Рубрика: Биологические науки

Статья в выпуске: 6 т.9, 2023 года.

Бесплатный доступ

Human beings have used plants as medicine for various health cause of years. Plants are widely used in the traditional medicine of different countries and are a source of strong drugs. To evaluate research some bioactive properties of the extract of the Crocus cancellatus subsp. mazziaricus (Herb.) B. Mathew, 1982 the antioxidant activities of these extracts were analyzed by means of cleaning methods (DPPH, ABTS scavenging activity), β-carotene/linoleic acid test system and FRAP activity. Phenolics and flavonoid contents as the equivalents of gallic acid, quercetin respectively. The phenolic content of the extracts was analyzed using HPLC. Brine shrimp lethality test was applied to analyze cytotoxic activity. The obtained results indicated that the highest phenolic compound ferulic acid with 2376.2±0.00 µg/g was in extracts. The highest total phenolic and flavonoid were found in the ethanolic extracts. The aerial part-methanol extract exhibited the highest antioxidant capacity and the corm acetone extract the highest amount of ferric reducing power activity. Among the four different extracts, the acetone extract showed the highest amount of radical scavenging both corm and aerial parts. The brine shrimp lethality assay of bulb ethanol extract has showed good cytotoxic with LC50 of 320.535 μg/mL. This study will be a source for future studies.

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Antioxidants, bioactive properties, radical scavenging activity, hplc

Короткий адрес: https://sciup.org/14127996

IDR: 14127996   |   DOI: 10.33619/2414-2948/91/04

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