24-hour blood pressure profile in chronic cerebrovascular diseases and sleep-disordered breathing

Arterial hypertension (AH) in patients with sleep-disordered breathing (SUB) is characterized by a higher level of blood pressure, increased variability and impaired circadian rhythm of blood pressure. The goal of the paper is to establish the changes in 24-hour blood pressure profile in patients with chronic cerebrovascular diseases and sleep-disordered breathing to optimize antihypertensive therapy. Materials and Methods. The trial enrolled 100 patients with chronic cerebrovascular diseases; the average age was 65 years (58.0; 74.5). Arterial hypertension was detected in 92 % of patients. All patients underwent 24-hour blood pressure monitoring. Cardiorespiratory monitoring was performed to verify sleep-disordered breathing. The authors also determined Apnea Hypopnea Index (AHI), saturation, and the duration of apnea episodes. Results. Patients with moderate and severe sleep-disordered breathing (AHI>15) demonstrated an increased systolic blood pressure (SBP) within 24 hours, an increased diastolic blood pressure (DBP) at night (p