Correlation between epicardial adipose tissue and structural and functional parameters of post-infarction myocardium in patients with coronary stenting

Available literature contains limited data on the correlation between epicardial adipose tissue and postinfarction myocardial remodeling with regard to diagnosis and prognosis. Objective. The aim of the paper is to study the correlation between epicardial adipose tissue thickness and structural and functional heart parameters in patients with myocardial infarction and percutaneous coronary intervention. Materials and Methods. The study involved 94 patients with myocardial infarction and subsequent ad-hoc percutaneous coronary intervention. All the patients underwent stress echocardiography 6 weeks after coronary stenting. Student's t-test, Mann-Whitney U-test, and sign test were used for statistical data processing. Results. The authors revealed significant differences in the parameters of the ejection fraction and the shortening fraction while assessing the systolic function of the left ventricle (LV). Patients whose epicardial adipose tissue thickness (EATT) was more than 3.5 mm demonstrated lower parameters. Assessment of the correlation between diastolic function and EATT showed that patients with EATT (>3.5 mm) had a longer time of LV isovolumetric relaxation (p3.5 mm compared with those with EATT3.5 mm demonstrated an increase in the end-diastolic LV dimension from 53.8 to 55.9 mm (p3.5 mm) in patients with percutaneous coronary intervention is associated with higher values of LV end-diastolic dimension, indexed left atrial volume and LV myocardial mass associated with lower values of LV ejection fraction and shortening fraction. Epicardial adipose tissue (>3.5 mm) in patients with post-infarction myocardial remodeling is associated with post-load increase in the LV end-diastolic dimension.