Taurine and/or camel milk mitigates haemolysis and malondialdehyde concentration in Alzheimer rats

Автор: Abdulkadir T.S., Ayo J.O., Isa A.Sh., Dawud F.A., Dimka-bashok L., Jafar F.Y.

Журнал: Журнал стресс-физиологии и биохимии @jspb

Статья в выпуске: 4 т.19, 2023 года.

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Alzheimer’s disease (AD) is a devastating neurodegenerative disease, affecting all age groups. Malondialdehyde (MDA) concentration and haemolysis are important oxidative stress biomarkers, implicated in the pathogenesis of AD. The study aimed to evaluate taurine, camel milk (CM) and their combined effects on MDA concentration and haemolysis in AD rats. The animal groupings were; Normal saline (0.2 mL/mg bw); AlCl3 (100 mg/kg); CM (33 mL/kg); Taurine (50 mg/kg); AlCl3 (100 mg/kg) + CM (33 mL/kg); AlCl3 (100 mg/kg) + Taurine (50 mg/kg) and AlCl3 (100 mg/kg) + CM (33 mL/kg) + Taurine (50 mg/kg). Concentration of MDA and percentage haemolysis were determined for all groups. At 0.5% NaCl, haemolysis in AD rats (64.00 ± 1.27 %) was higher ( p

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Aluminum chloride, camel milk, malondialdehyde, taurine, oxidative stress

Короткий адрес: https://sciup.org/143180987

IDR: 143180987

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