Течение каловых масс в толстом кишечнике: биомеханика, реология, моделирование
Автор: Шмурак М.И.
Журнал: Российский журнал биомеханики @journal-biomech
Статья в выпуске: 4 (98) т.26, 2022 года.
Бесплатный доступ
Моделирование - это возможность реализовать функционал живого органа и проанализировать влияние различных факторов на него. В частности, моделирование движения каловых масс по кишечнику позволяет нам исследовать взаимосвязь между моторикой и обработкой кишечного содержимого, временем его прохождения и перистальтическими волнами. Кишечник представляет собой систему сложной геометрической формы, с волновыми движениями разных конфигураций и многоуровневой обработкой внутреннего содержимого. В то же время медицинское исследование индивидуальных особенностей его строения и функции занимает довольно много времени. Построение персонализированной модели, учитывающей все эти факторы, является нетривиальной задачей. Однако такая модель (если ее удастся разработать) сведет к минимуму использование инвазивных оценок состояния пациента. Моделирование также может быть использовано в качестве основы для планирования терапевтических мероприятий для конкретного пациента. Представлен обзор современных математических моделей, разработанных за последние пару десятилетий для моделирования движения каловых масс по толстой кишке.
Толстая кишка, моделирование, реологические свойства, гиперупругость, анизотропия, перистальтические волны
Короткий адрес: https://sciup.org/146282612
IDR: 146282612 | DOI: 10.15593/RZhBiomeh/2022.4.06
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