Test-model and quantitative RDDS criterion index which are applied to estimate antimicrobic potential of nanomaterials used for water purification and treatment: substantiation and metrologic assessment

To reduce population health risks which occur when people consume drinking water from centralized water supply systems is a vital medical-biologic and technical problem. It can be sold, among other things, via development and application of new materials for water purification and treatment. Some natural and artificial nanomaterials have antimicrobic properties as they can eliminate microorganisms of various taxonomy (bacteria, yeast-like and mold fungi) and bacterial biofilms. However, certain results which were obtained when antimicrobic potential of nanomaterials was estimated are controversial; they are frequently only qualitative or semi-quantitative due to absence of a standard test protocol and well-grounded criterial assessment apparatus. So, the goal of this paper was to give methodological grounds and to create a unified and standardized test-model; to optimize parameters of a procedure and to substantiate a system of criteria applied for quantitative assessment of antimicrobic activity which is characteristic for nanomaterials applied for water purification and treatment...