The acute effect of running exercise on liver ABCA1 gene expression in male Wistar rats
Автор: Seyed Morteza Tayebi , Mitra Khademosharie , Tayebe Amiri Parsa , Mehdi Abaszadegan , Ayoub Saeidi , Nenasheva A.V.
Журнал: Человек. Спорт. Медицина @hsm-susu
Рубрика: Физиология
Статья в выпуске: S1 т.19, 2019 года.
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Objectives. ATP-binding cassette transporters transfer a variety of substrates across the lipid bilayers in an energy-dependent manner. ABCA1 is a member of this family, which plays a crucial role in plasma HDL-C metabolism. On the other hand, the short-term effects of exercise training are less studied. The aim of this study was the effects of a single bout of exercise on liver ABCA1 gene expression in the male Wistar rats. Methods. Twenty four male Wistar rats were housed in a standard environment and randomly divided into two Control (n = 12) and Experimental (n = 12) groups. The exercise included running on a treadmill for 120 min (18 m/min). Immediately, 2 and 24 hours after exercise, rats were anesthetized, and samples were taken from the adipose tissue and liver. Liver ABCA1 was assessed by RT-PCR. Results. The results showed that liver ABCA1 gene expression had significant elevation immediately, 2 and 24 hours after exercise (p
Abca1, gene expression, exercise, liver, adipose tissue, wistar rats, крысы породы wistar
Короткий адрес: https://sciup.org/147233707
IDR: 147233707 | DOI: 10.14529/hsm19s106
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