Effect of aminoglycoside antibiotics on mitosis pathology in Allium-test

Автор: Kantsavaya Irina, Alekseenko Olga

Журнал: Бюллетень науки и практики @bulletennauki

Рубрика: Биологические науки

Статья в выпуске: 3 т.6, 2020 года.

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The research work examines the effects of aminoglycoside antibiotics (gentamicin, streptomycin, canamicin, amycatin) and cytokinin 6-BAP on the pathology of mitosis in Allium-Test. Research methods: Allium-test, cytogenetic analysis, statistical analysis. Test results of aminoglycoside antibiotics showed an increase of 1.3-3.0 times pathological mitosis in the cells of meristematic tissue of onion roots compared to control in variants of gentamicin in concentrations of 50.0 and 100.0 mg/l and streptomycin - 150.0 and 1000.0 mg/l. At the same time, the use of kanamycin in concentration of 100.0 and 1000.0 mg/l and amicacin of 500.0 mg/l inhibits pathological processes in cells. When considering phase indices, the induction of aminoglycoside antibiotics of mitosis pathology such as mitosis delay in metaphase is noted, which is related to damage to the mitotic apparatus. In the examination of phase indices, induction of aminoglycoside antibiotics of mitosis pathology such as delay of mitosis in metaphase, which is associated with damage to the mitotic apparatus...

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Allium-test, aminoglycoside antibiotics, mitosis pathology

Короткий адрес: https://sciup.org/14116023

IDR: 14116023   |   DOI: 10.33619/2414-2948/52/07

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