Influence of hyperbaric oxygenation on electrophysiological characteristics of myocardium

The objective of the paper is to study the influence of hyperbaric oxygenation (HO) on some electrophysiological characteristics of the myocardium. Materials and Methods. The study involved 30 patients (21 males and 9 females, their average age was 59±16.1) with coronary artery disease and arterial hypertension (stages 1-2) complicated by chronic cardiac insufficiency I-II FC, before and after 5-day HO regimen. Studies included detection of QT dispersion on a 12 lead surface ECG and parameters of heart rate variability (HRV) - HF, LF, VLF, HF/LF. Results. The analysis of ECG results revealed that all patients who initially had VLP did not demonstrate any qualitative improvements after 5-day HO regimen. The average values of depolarization parameters did not show any favourble improvement. At the same time, three out of five patients (10 % of the total number) without VLP demonstated its signs after the abovementioned procedure. The ECG results showed that the QT dispersion decreased by 14 % (from 83.4 to 69.5 ms) after HO regimen. Moreover, it was evident in males (from 80.9 to 63.6 ms). These changes may indicate the improvements in ventricular repolarization processes. HRV results indicate that HO regimen does not singnificatly affect the autonomic nervous system. Conclusion. HO regimen provides multidirectional influence on the processes of depolarization and repolarization of the ventricles. At the same time, HO regimen does not have a significant impact on the variability of the heart rate.