Influence exerted by Helicobacter pylori on concentrations of anti-inflammatory Т-cell cytokines and sunpopulations that produce them

Helicobacter pylori is a widely spread pathogenic microorganism. It penetrates the mucous tunic of the stomach and the duodenum and causes diseases in the gastrointestinal tract, including oncologic ones. This agent is able to be chronically persistent in a body and frequently there are no apparent symptoms of it; therefore, it is difficult to detect this pathogen in due time. Risk analysis related to occurrence and development of various pathologies associated with Helicobacter pylori, revealed that their clinical course was to a great extent determined by an immune response that emerged after infection. There are data that Helicobacter pylori is able to influence protective immune reactions making their balance to move to an increase in immune-suppressive components, for example, increased concentrations of T-regulatory cells and cytokines produced by them. However, some data can be found on Helicobacter pylori ability to induce anti-inflammatory responses which include those associated with T-helpers of the 1st and 17th types...