The influence of nonglycosidic inotropic stimulation and binary neurohumoral unloading on the intensity of endothelial dysfunction and chronic cerebral ischemia in elderly people with myocardium infarction

The aim was to study levosimendan inotropic stimulation influence on endothelial function and cognitive impairment severity in myocardial infarction of aged patients with acute heart failure signs. The study involved 38 aged patients with myocardial infarction complicated by acute heart failure. All patients received combined conservative therapy. Moreover, 20 patients have got levosimendan according to the standard scheme. According to the results of testing in this group the improvement of endothelial and cognitive functions was shown, whereas in the comparison group such results were not achieved. These data allowed us to conclude that levosimendan has favorable influence on endothelial function and cerebral blood flow.