Possibilities of pharmacological correction pathogenetic factors of age-associated changes in the bladder

Introduction. Aging is a complex biological phenomenon that encompasses all organs and systems of the human body, including the urinary system. The theory of inflammatory aging suggests that the senescence process is accompanied by the formation of chronic inflammation, activation of oxidative stress and the production of inflammatory or profibrotic cytokines, which ultimately leads to fibrotic tissue transformation and the development of functional organ deficiency and, in particular, plays a key role in age-associated bladder restructuring. With this in mind, it seems promising to study the possibilities of medicinal effects on the above-mentioned factors of preparations with proven anti-inflammatory and antioxidant activity.