Opportunities of neuroprotective therapy for perinatology

A new approach to neuropsychic health gain in children is to ensure optimal perinatal neuro-ontogenesis development. The relevance of this problem is associated with the increase in the number of premature babies and those with perinatal pathology. The authors search for early causes of neurological deviant development since the perinatal period. Chronic intoxication, somatic and infectious pathology, malnutrition during pregnancy, and pregnancy disorders are among these causes. The work describes modern pathomorphosis of perinatal brain damage due to preterm birth, germinal matrix persistence, subependymal and intraventricular hemorrhages. Much attention is paid to early prevention of retardation in neuropsychic development, beginning with the perinatal period. The syndrome neuro-cardio-respiratory depression in fetus and newborn is described. The article presents modern data on the possibilities of complex neuroprotective therapy in perinatology in order to ensure the physiological flow of perinatal neuro-ontogenesis in preterm and full-term infants. The authors present their own data on maternal history in 90 women with preterm delivery at low gestational age and on cerebral blood flow in extremely preterm infants under the development of intraventricular hemorrhage (grade 1). They also touch upon the problems dealing with administration of pharmacological neuroprotective agents and natural metabolites. The article presents new data on neuroprogramming role of nutrition in the perinatal period.