Вторые опухоли у лиц, подвергавшихся противоопухолевой терапии в детском возрасте. Статистика, этиология, пути профилактики

Автор: Щербенко Олег Ильич

Журнал: Вестник Российского научного центра рентгенорадиологии Минздрава России @vestnik-rncrr

Статья в выпуске: 3 т.13, 2013 года.

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Проведен анализ литературы, посвященной отдаленным последствиям противоопухолевого лечения у детей и подростков. Констатировано, что в отдаленные сроки после излечения первичной опухоли основными проблемами становятся вторые опухоли и сердечно-сосудистая патология. Основным фактором индукции вторых опухолей является лучевая терапия. Вероятность развития последствий терапии находится в прямой корреляции с величиной дозы облучения и временем, прошедшим после лечения. Результаты анализа свидетельствуют о целесообразности пересмотра показаний к проведению консолидирующей лучевой терапии, с отказом от нее в случаях благоприятного прогноза и полной регрессии опухоли в результате операции или химиотерапии. При наличии необходимости в лучевой терапии лечение должно проводиться в максимально щадящем режиме с применением стереотаксических методик, современной радиотерапевтической аппаратуры и в минимально возможных дозах. Больные, получавшие противоопухолевую терапию в юном возрасте, должны находиться пожизненно под диспансерным наблюдением онкологов с особым вниманием к зонам, подвергавшимся облучению.

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Опухоли у детей, отдаленные последствия, лучевая терапия, радиационный канцерогенез

Короткий адрес: https://sciup.org/14955408

IDR: 14955408

Список литературы Вторые опухоли у лиц, подвергавшихся противоопухолевой терапии в детском возрасте. Статистика, этиология, пути профилактики

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