Interrelationships of nosogenic mental reactions and personality disorders with pre-illness personality traits in female patients with breast cancer

Registered getting younger of breast cancer (BC), high frequency of its diagnosis, survival rate of patients in connection with the improvement of methods of therapy of BC lead to increase in the number of female patients with nosogenic mental disorders. In this regard, particular relevance is acquired by detailed study and differentiated approach to the study of the manifestations of mental disorders at various stages of breast cancer based on clinical typology of psychosomatic correlations and evaluation of the contribution of constitutional features. The paper examined two groups of patients with BC: group 1 : patients with psychopathological disorders (F40-F48 neurotic stress-related and somatoform disorders according to ICD-10); group 2: patients with signs of pathological dynamics of personality disorders (F62 according to ICD-10) against the background of a long course of BC. Nosogenic mental disorders in breast cancer are clinically heterogeneous and are represented by two nosological categories: nosogenic reactions and pathocharacterological personality developments. Nosogenic reactions in breast cancer are formed at the early hospital stage according to mechanisms of reactive anxiety states with comorbid psychopathological disorders of neurotic and affective registers that determine their clinical differentiation into 3 main types of clinically completed types: anxiety-depressive, anxiety-dissociative and anxiety-hypomanic ones. Pathocharacterological developments of personality are formed at the distant follow-up stage of BC and show substantial clinical heterogeneity.