The importance of inflammatory processes in the pathogenesis of atrial fibrillation in patients with ischemic heart disease

The objective of the study was to estimate the levels of C-reactive protein, serum interleukin 1β, and tumor necrosis factor-α in patients with coronary heart disease (CHD) and different forms of atrial fibrillation (AF). The study surveyed a total of 113 patients aged 49.6+2.8 years with a primary diagnosis of coronary artery disease. Data demonstrated a link between the levels of proinflammatory cytokines in patients with coronary artery disease and the number of seizures and arrhythmias. The study reliably showed that the higher levels of TNF-α and IL-1β in the serum are associated with the higher frequency of AF episodes.