Биомаркеры острого инфаркта миокарда: диагностическая и прогностическая ценность. Часть 2 (обзор литературы)

Автор: Чаулин Алексей Михайлович, Дупляков Дмитрий Викторович

Журнал: Клиническая практика @clinpractice

Статья в выпуске: 4 т.11, 2020 года.

Бесплатный доступ

Во второй части обзора мы продолжаем начатое ранее обсуждение биомаркеров, имеющих диагностическое и прогностическое значение при остром инфаркте миокарда (ОИМ). Изучение патогенетических механизмов ОИМ путем экспериментальных и клинических исследований способствует открытию новых регуляторных молекул, которые будут использоваться в качестве эффективных биомаркеров для диагностики и прогнозирования ОИМ. В частности, подробно рассматривается диагностическая и прогностическая ценность известных воспалительных биомаркеров - С-реактивного белка, интерлейкина-6, фактора некроза опухоли альфа, миелопероксидазы, матриксных металлопротеиназ, растворимой формы лиганда CD40, прокальцитонина, плацентарного фактора роста, а также ряда недавно открытых биомаркеров ОИМ - кардиоселективных микроРНК; галектина-3; стимулирующего фактора роста, экспрессируемого геном 2; ростового фактора дифференцировки 15; пропротеиновой конвертазы субтилизин-кексинового типа 9.

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Лабораторная диагностика, острый инфаркт миокарда, оим, биомаркеры, с-реактивный белок, интерлейкин-6, фактор некроза опухоли альфа, миелопероксидаза, матриксные металлопротеиназы, прокальцитонин, микрорнк, галектин-3, пропротеиновая конвертаза субтилизин-кексинового типа 9

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Короткий адрес: https://sciup.org/143175833

IDR: 143175833 | DOI: 10.17816/clinpract48893

Список литературы Биомаркеры острого инфаркта миокарда: диагностическая и прогностическая ценность. Часть 2 (обзор литературы)

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